The No. 25 Louisville Cardinals (7-4) will look to continue their strong finish to the regular season when they take on the Kentucky Wildcats (6-5) in Saturday afternoon’s 2022 Governor’s Cup. Louisville pulled off a 25-10 win over NC State despite playing without their star quarterback. Kentucky is riding a two-game slip, but it put on a competitive effort against No. 1 Georgia last week.

Kick-off is scheduled for 3:00 p.m. ET from Lexington, Kentucky. The Wildcats are favored at 3 points in the latest Kentucky vs. Louisville odds from Caesars Sportsbook, while the over/under is fixed at 43. Before you participate in Louisville vs. Kentucky tips, you’ll want to see the model’s college football predictions at SportsLine.

The SportsLine projection model simulates every FBS college football game 10,000 times. For the last 6+ years, the proprietary computer model has generated a staggering nearly $3,000 in profits for $100 players using its top-flight college football picks against the spread. Everyone who has followed it has seen huge returns.

Now the model has Kentucky vs. Louisville in her sights. You can go to SportsLine to see the selection. Here are several college football odds for Kentucky vs. Louisville:

  • Spread between Kentucky and Louisville: Kentucky -3
  • Kentucky vs. Louisville over/under: 43 points
  • Monetary border between Kentucky and Louisville: Kentucky -155, Louisville +130
  • Kentucky vs. Louisville selection: See selection here

Featured Game | Kentucky Wildcats vs. Louisville Cardinals

Why Kentucky can cover

Kentucky has lost three of its last four games, but is coming off one of its best games of the season. The Wildcats were underdogs on 22.5 points but only conceded a touchdown in the 16-6 loss to Georgia. Running back Chris Rodriguez Jr. rushed for 51 yards while quarterback Will Levis threw for 206 yards and a point.

Freshman wide receiver Barion Brown amassed 560 receiving yards and three touchdowns in the loss. Louisville has lost several games as a favorite this season, so the Cardinals aren’t worth supporting as short underdogs. Kentucky has won four of the last five meetings between these teams, covering the span.

Why Louisville can cover

Louisville enters this competition with a lot of momentum, having won five of their last six games. The Cardinals beat NC State 25-10 last week despite being without quarterback Malik Cunningham. He could return for this game, but junior signal caller Brock Domann has won both of his games as a starter this year.

The Wildcats have won 2-5 in their last seven games, including multiple blowout losses. Louisville has shown a lot of defensive improvements this year, rising from 83rd to 37th in overall defense since last season. This is expected to be a close game, which is why it’s important to have Louisville kicker James Turner, who was named ACC co-specialist of the week after setting a school record with four field goals against NC State.

How to make Kentucky vs. Louisville picks

The model has simulated Louisville vs. Kentucky 10,000 times and the results are in. We can tell you that the model is leaning forward and it also generated a point spread pick that hits well over 50% of the simulations. You can only see the selection at SportsLine.

So who will win Kentucky vs. Louisville? And which side of the spread applies well over 50% of the time? Visit SportsLine now to see which side of Saturday’s Kentucky vs. Louisville spread you need to jump to, all from the model who crushed his college football picks and find out.